REVIEW ARTICLE
A Narrative Review: Exercise Induces Adipose Browning by Altering the Gut Microbiome Profile
Dini Suryani1, 2, Vita Murniati Tarawan3, Imam Megantara4, Ronny Lesmana3, 5, Nova Sylviana3, 5, Hanna Goenawan3, 5, *
Article Information
Identifiers and Pagination:
Year: 2022Volume: 15
E-location ID: e1875399X2211210
Publisher ID: e1875399X2211210
DOI: 10.2174/1875399X-v15-e221125-2022-28
Article History:
Received Date: 24/06/2022Revision Received Date: 14/10/2022
Acceptance Date: 20/10/2022
Electronic publication date: 29/12/2022
Collection year: 2022

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Obesity is a condition that is highly associated with chronic diseases. The number of obese individuals is increasing on a global scale every year. Energy intake that is imbalanced with energy expenditure causes the accumulation of excess fat. Regular exercise is part of a lifestyle that can reduce the risk of obesity by inducing adipose browning. One of the mechanisms of exercise in inducing browning is by modifying the gut microbiome profile. This profile may promote adipose browning by maintaining the integrity of the intestinal barrier, glucose homeostasis, regulating energy absorption, and appetite-regulating hormones.