Sedentary behavior is one of the strongest risk factors for many chronic diseases and conditions, including cardiovascular disease, hypertension, diabetes, obesity, osteoporosis, colon cancer, and depression [1]. It has been found that involvement in physical activities may significantly reduce other risk factors for atherosclerosis. The World Health Organization 2020 issued the same statement in the wake of the global pandemic of COVID-19 that physical exercise is necessary during the lockdown as this may reduce other risk factors for atherosclerosis (e.g., blood lipid abnormalities and elevated blood pressure levels) [1], and thereby decrease the risk of macrovascular or atherosclerotic complications of diabetes [2], [3].

Initial studies found increased severity of coronavirus disease 2019 (COVID-19) [4], caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients with diabetes mellitus. Furthermore, COVID-19 might also predispose infected individuals to hyperglycemia [5]. Many researchers have opined that regular physical activity decreases the risk of cardiovascular disease mortality [3, 4] in general and of coronary heart disease mortality in particular [3, 5, 6]. Hence, it was advised to prevent such complications among patients with diabetes mellitus who are at risk of SARS-CoV-2 infection and that they should try not to be sedentary for long periods, as regular physical activity is associated with decreased incidence of thromboembolism [4, 7]. Instead, these individuals should try to engage in physical activity to improve blood circulation [8].

College students, generally late adolescents (who are in the age of transition from childhood into self-sufficient adulthood), go through many physical and mental changes that may have positive and negative influences on their lives [5]. It is observed that participation in regular physical activity during this transitionary period assists college students in coping with stress, aiding their transition into self-sufficient adulthood [9]. This is more necessary as physical activity/physical exercise (PA/PE) rates tend to decline precipitously during the secondary school years, leading to low physical activity and exercise (PA/PE) among undergraduate and college males and females [10, 11]. Prevalence rates show that adolescent girls are less active than boys [12, 13], and that activity declines more precipitously among girls during adolescence [12, 14]. There are many socio-demographic and cultural factors, such as age, marital status, income, diet/food/meal pattern, socio-cultural factors, technology and social affluence [15] that could predispose adolescents to lack of participation in PA/PE and could finally predispose the individual to develop health problems, including cardiovascular diseases.

Approximately one-third of children in Nigeria are overweight or obese. It has been observed [6, 16] that there is also a trend of low involvement of college students in physical activities, which may lead to obesity [17]. Children (particularly adolescents) need a positive behavioral change toward weight control, as obese individuals may also suffer

from social stigmatization, discrimination [7], and lower self-esteem [8]. Overweight and obesity (including childhood obesity) substantially raise the risk of illnesses, including high blood pressure, high cholesterol, type 2 diabetes, heart disease, stroke, gallbladder disease, arthritis, sleep disturbances, cardiovascular disease, hypertension, osteoporosis, colon cancer, depression [9], and certain types of cancers [8].

Regular physical activity and physical fitness contribute to one’s overall health [14], sense of well-being [12], and maintenance of healthy body weight [15]. Participation in PA/PE also promotes long-term health and well-being [16], [17], reducing the risk of obesity and type 2 diabetes among young people [8, 18, 19]. However, only a few adopt physical exercise as a means of promoting health [19-20]. Due to low or no involvement in PA/PE, the prevalence of obesity is increasing at an alarming rate among young people [20, 21]. Because of an increase in the drop rate of participation in PA/PE, the adolescents are advised to spend at least 30 minutes of moderate activity on five [10] or more days per week or twenty minutes of vigorous activity three or more times per week [22, 23]. It has been recommended that an appropriate exercise program is added to the diet or drug therapy that will improve blood glucose control and reduce certain cardiovascular risk factors among persons with diabetes [11, 24, 25]. The undergraduates may not know that they are at risk of such diseases as diabetes [11, 17, 20], high blood pressure, arteriosclerosis, arthritic situations, and burden of cardiovascular diseases, or invariably if they are at a high risk of total breakdown from these debilitating diseases [26], or associated diseases if proper care is not taken [26].

The World Health Organization [1, 8] states that exercise training may reduce other risk factors for atherosclerosis (e.g., blood lipid abnormalities and elevated blood pressure levels). PA helps decrease the risk of macrovascular or atherosclerotic complications of diabetes [14]. Lastly, physical activity may prevent or delay the onset of non-insulin-dependent diabetes mellitus (NIDDM) [24, 27, 28] by reducing total body factors, specifically intra-abdominal fat, a known risk factor for insulin resistance [20]. Physical activity is inversely associated with obesity [29] and intra-abdominal fat distribution, and recent studies have demonstrated that physical training can reduce these body fat stores [25, 30]. Much of the effect of physical activity appears to be due to the metabolic adaptation of skeletal muscle. However, exercise training may contribute to improved glucose disposal and glucose-insulin dynamics in both adipose tissue and the working skeletal muscles. Diet and exercise have been found to be most effective for controlling NIDDM in persons who have mild disease and are not taking medications [12, 25, 26]. There is a need to assess the predictive factors (socio-demographic factors) affecting involvement in PA, the time spent on it, the intensity and involvement in sustained participation in physical activities/exercises of the freshmen of Babcock University in order to improve the general wellbeing, wellness and health status of the students and militate against cardiovascular diseases. Hence, this study assessed the effects of socio-demographic factors and physical exercise training on cardiovascular health by carrying out a case study of fresh students of Babcock University Ilishan-Remo, Ogun State, Nigeria.

The post-test showed a significant increase in physical activities and a corresponding decrease in physical inactivity. The comparison of the participants who got involved in physical exercises that increased breathing at the baseline and the post-test indicated an increase from 105 (17%) to 174 (29%) among those who exercise one or two times per week. There was a great change observed among those who exercised six times a week or more per week, from 33(5.5%) to 156 (26.0%) (Fig. 3). The changes in outcome variables across time for the group had a significant interaction effect on the time for perceived benefits, social support, counter conditioning (an induced condition in humans in which behavior is incompatible with a habitual undesirable pattern), and overall time spent being active per week and on PA (mean minutes per day), indicating that the pre and the post results differed across time.

Fig. (3). The result of the post-test showing the respondents involved in exercises that increase breathing rapidly.

From Tables 2 above and 3, the significance at 2=tailed for all the variables in relation showed the mean arterial pressure (MAP) (classified as low MAP, normal MAP, and high MAP) to be greater than 0.05. Hence, there was no significant difference observed between the mean ages, blood sugar level, body temperature, and the body mass index of patients with low, normal, and high MAP. It could be deduced that the mean arterial pressure is not affected by the age, blood sugar level, body temperature, and body mass index of this group of students.

Figs. (4 and 5) show the bar chart of the body mass index and the mean arterial pressure (Table 3).

The results from Figs. (4 and 5) show a bell-shaped curve. The bell-shaped curve is normal and presents normally distributed data. Thus, the data for all the variables are normally distributed.

Table 4 shows the frequency of the pre-medical examined variables. The result shows that many, 25 (33.8%), were obese, those who were classified as having overweight were 20 (27.1%), 16 (21.6%) had prediabetes tendency, and the temperature was normal in 44 (59.5%), and the mean arterial pressure (MAP) was also normal in many, i.e., 55(74.3), of the respondents. Fig. (6) below shows the time spent on vigorous activities. The highest time spent was an average of 16 to 30 minutes, with 261 (43.5%) respondents.

Many, 56%, were not on a usual health maintenance drug; however, 27.5% used a drug at least once, while 14.6% said that they used a health maintenance drug at least twice or thrice. 17% of the respondents were diabetic, while only 60 (10%) were having high blood pressure, as shown in Table 5.

Fig. (4). The bar chart of the body mass index.

Fig. (5). The bar chart of the mean arterial pressure.

Fig. 6. Time period spent on the vigorous activity at the baseline.

From Table 5 above, we can say that the effect of the combined social demographic characteristics and physical exercise showed a weak positive correlation between the gender and the BMI of the patients as the r-value was 0.273 and p=0.027 at 0.05 level (2-tailed). P-value was less than 0.05, so there existed a correlation. There was a weak negative correlation obtained between the ages of patients and their body temperature as the r-value was -.286 and p-value was 0.019, and it was significant at the level of 0.05 (2-tailed). There was also a weak positive correlation obtained between the ages of the patients and their mean arterial blood pressure as the r-value was 0.319 and p=0.006 at 0.01 level (2-tailed).

Table 6 above shows the respondents’ parental health status. The table shows the social determinants of health, which are a predisposing factor to the possibility of developing certain genotypic characteristics being transferred from parent to their offspring. The result is an indicator of the futuristic probability of possible susceptibility to cardiovascular diseases, as reported by the respondents. The result showed many, 236 (39.3%), to affirm that none of their parents had any of the diseases. On the other hand, almost the same, i.e., 234 (39%), said that both of their parents have one cardiovascular health-related disease or another.

Table 7 shows the changes in outcome variables across time for each of the two independent variables, which are the correlates of socio-demographic factors and physical exercise training with respect to cardiovascular performance and health status among 600 volunteered freshmen of Babcock University. There were significant interaction effects observed between the two variables, which are the correlated socio-demographic factors and physical exercise training, perceived benefits, self-efficacy, interpersonal norms, social support, counter conditioning, stimulus control, overall time spent being active per week and on PA (mean minutes per day), indicating that the groups differed across time. Main effects tests for the group at post-intervention, with the baseline values as a covariate, revealed significant differences for counter conditioning, F = 59.276, with the mean score within group 1.60, df 2, p = .000, R = -282, and the overall minutes of those who said that they can do PA per week =2.30

The comparison of the baseline and the post-test showed an increase in the number of times of involvement in PE as respondents participated one to two times per week, ranging in number from 105 (17%) to 174 (29%). Females dropped out of organized physical activity/sport [9, 21]. Almost 50%, 321(53.5%), of females dropped more than males; the reason provided by them was that they had too much coursework. This finding was found to be the same as that reported earlier [4]. The effect of the combined social demographic characteristics and physical exercise showed a weak positive correlation between the gender and the BMI of the patients as the r-value was 0.273 and p=0.027 at 0.05 level (2-tailed). This was corroborated in a previous research [14] that demonstrated a positive relationship between participation in physical exercises by in-school adolescents [33] and their overall health and educational development [34]. There were significant interaction effects found between groups and time for perceived benefits, interpersonal norms, social demographic interaction, counter heart conditioning, stimulus control, overall time spent being active per week and on PA (mean minutes per day), indicating that the groups differed across time. This was in line with two different school-based studies [16] that reported improvements in physical activity rates in children and adolescents exposed to the intervention that involved spending more time on moderate to vigorous physical activity with results across studies ranging from 5 to 45 minutes; the participants had improved VO2max (volume of oxygen maximum intake) and exhibited increased daily physical activity and improved metabolic health. These findings also show that the tests of the main effects for the group at post-intervention, with the baseline values were taken as covariates, revealed significant differences for counter conditioning, with F = 59.276, mean score within group as 1.60, df 2, p = .000, R = -282, and the overall minutes of those who can do PA per week =2.30 [28, 29].

There was a positive relationship obtained between knowledge and participation in physical exercises by the respondents and their overall health and educational development; the same findings have been reported by many researchers [12, 30, 31, 33], who have reported a similar trend of increment in the relationship between the increase in knowledge and physical activity because of intervention involving physical activity courses taken by the college students.

The primary “take-away” lessons of this case report were that the participants were aware of the relationship between physical activities and their health. The knowledge mean score at the baseline was 19.57+ 6.12, and the knowledge mean score was 21.78± 5.36 on a 27-point scale (Table 1c), which increased greatly post-report. The result showed significant covariate differences for counter conditioning, with F = 59.276. The mean score within groups was reported at 1.60, df 2, p = .000, R = -282, and the cue to action showed an increase in the overall minutes of those who said they could do PA per week. Based on the outcome of this study, school administrators and policymakers should note the enormous contributions of PE interventions that they play a very significant role in determining the student's involvement in physical activities and also generate information that can be used to design an appropriate policy framework for implementing effective physical exercise in tertiary institutions and stimulating policy formulation or facilitating necessary curricular review, aimed at promoting young persons’ participation in physical activities for the purpose of maintaining good health status. It is thus concluded that socio-demographic factors and physical activity training have a significant effect on cardiovascular diseases and signs that predate cardiovascular diseases. Therefore, the students’ involvement, especially the undergraduate students of Babcock University, in physical activities through absolute incorporation of them into the curriculum of higher learning is an essential part, which can help maintain their adequate health status [13].

It is necessary to consider the scientific reason for this study and the strengths associated with this case report. It has been recommended that an appropriate exercise program, if added to the diet or drug therapy [20] along with the intervention of physical activities and exercise program, will help improve blood glucose control [35, 36] and reduce certain cardiovascular risk factors among persons with diabetes [2, 11]. The undergraduates may not have known that they are at risk of such diseases as diabetes, high blood pressure, arteriosclerosis, arthritic situations, and burden of cardiovascular diseases, or invariably at a high risk of total breakdown from these debilitating diseases or associated diseases if proper care is not taken [11]. However, this study has associated limitations that include a lack of funds, duration being limited to six weeks, which may have led to a lack of accommodation of the proper monitoring of the subjects, thereby reducing the dropouts, as well as performing only immediate post-intervention.

Based on the outcomes of the study, sedentary or lack of physical inactivity is a major risk factor for CVD and that moderate levels of regular physical activity confer significant health benefits; thus, the study provides the following recommendations:

All collegiate students should engage in regular physical activity at a level appropriate to their capacities, needs, and interests. Secondly, the university administrators should encourage physical activities by entrenching the physical education classes into the curriculum to motivate the young ones to adopt a preventive lifestyle that will reduce the illness burden in the university where heavy insurance is needed for the medical upkeep of the students in their colleges, institutions, and university. Thirdly, apart from the Health Principle course, there should be the introduction of zero unit seminars that may convert to compulsory participation in physical exercise of all students at all levels and which should reflect in the transcript of the students; finally, it is recommended that curriculum reviewer committees should include a professional and, in particular, a physical activity or exercise instructor to teach or train students in physical education courses.